Premium Methylene Blue
Known for its high-purity aqueous formulation, our 1% Methylene Blue USP Grade solution is manufactured to stringent quality standards. Designed for customers who value precision, consistency, and transparency, this product is produced using USP-grade raw materials and controlled processes to ensure reliability from bottle to bottle.
Each batch is carefully prepared and quality-checked to meet USP specifications, then packaged in a 60 mL cobalt blue glass bottle to help protect integrity and stability.
Key Features
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Concentration: 1% aqueous solution
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Grade: 99.99% USP/Pharmaceutical Grade, formaldehyde-free
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Volume: 2 oz (60 mL) - 2 month supply at dosage range listed on the bottle
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Packaging: Cobalt blue glass bottle to promote longer shelf life
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Quality Controlled: Manufactured in the USA in accordance with cGMP principles in an FDA certified facility.
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Purity Focused: Third-party lab tested for identity, purity & quality.
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COA available upon request: Email support@thistledewvitality.com.
- Crafted in the USA
Storage
Store in a cool, dry place away from direct light. Keep bottle tightly closed when not in use.
Caution Statement
See Link Below
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Suggested Use
Step 1: Start Small
Each drop contains 0.5mg of methylene blue. Begin with a low dose of 1-3 drops daily to assess tolerance. This allows your body to adjust to methylene blue gradually. Increase dosage as tolerated up to 20 drops/day. Consult with a healthcare professional to determine the right dose for your needs.
Step 2: Mix Well
Add drops to 12 oz of water or your favorite beverage. Avoid using coffee. Mix well before consuming to achieve optimal results. To prevent staining of teeth and mouth drink through a straw or put drops in an empty gel capsule (drink with 12 oz of water). If you have tooth colored restorations or dentures using an empty gel capsule is recommended.
Step 3: Take Daily
Consume in the morning or early afternoon as most users find methylene blue energizing. For long-term use cycle 5 days on with 2 days off or as directed by your healthcare professional. Maintain a regular schedule and stay properly hydrated throughout the day. Feel the energy!
ThistleDew Vitality
More Energy.
More Oxygen.
More Life.
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Frequently Asked Questions
What are the ingredients of your Methylene Blue?
Our pharmaceutical-grade liquid methylene blue contains ONLY pure USP-Grade Methylene Blue and Pure Reverse Osmosis Purified Water.
There are NO unnecessary additives —no binders, fillers, gelatin, artificial colors, sweeteners, or preservatives. All of which are found in capsules and gummies.
Is Methylene Blue a supplement or a synthetic medication?
Methylene Blue is a synthetic compound that has been used in medical settings for over a century. While it's synthetically produced, our pharmaceutical-grade Methylene Blue is formulated as a dietary supplement. It's manufactured in cGMP-certified facilities in the United States to ensure the highest quality and purity standards. This product is intended to support mitochondrial health and cellular energy production as part of a wellness routine.
What is the MITOCHONDRIA?
The mitochondria are the powerhouse of the cell - they're tiny organelles inside your cells that produce ATP (adenosine triphosphate), which is the energy currency your body uses for virtually every function.
Healthy mitochondria are essential for cellular energy production, cognitive performance, and overall vitality.
Methylene blue supports mitochondrial function by enhancing the electron transport chain, helping your cells produce energy more efficiently.
Why Choose LIQUID Methylene Blue over capsules or gummies?
Liquid methylene blue offers several key advantages over capsules and gummies:
Superior Absorption & Bioavailability Liquid form begins absorbing immediately in the mouth and continues through the digestive tract, allowing for faster and more efficient uptake compared to capsules that must first dissolve or gummies that contain fillers and sugars.
Precise Dosing Control With liquid drops, you can easily adjust your dose drop-by-drop to find your optimal amount. Our 1% Methylene Blue solution contains 0.5mg of methylene blue per drop making precision dosing easy. Capsules and gummies lock you into fixed doses, making it difficult to customize or gradually increase your intake.
Maximum Purity & Potency Liquid form maintains the highest concentration and purity of methylene blue without degradation from heat, compression, or mixing with other ingredients required in capsule and gummy manufacturing.
Is any type of Methylene Blue safe for human consumption?
No, not all methylene blue is the same.
ONLY pharmaceutical-grade methylene blue (USP grade) that meets strict purity standards can be safe for human consumption when used appropriately. However, not all methylene blue is created equal—industrial or laboratory-grade methylene blue may contain impurities and should never be consumed.
Key considerations:
- Only use USP (United States Pharmacopeia) pharmaceutical-grade methylene blue
- Follow recommended dosing guidelines carefully
- Consult with a healthcare provider before use.
Our methylene blue products are pharmaceutical-grade, third party tested and manufactured to the highest purity standards for safe consumption.
We strive to keep our pricing affordable to our customs. Be very cautious of companies selling online at unusually low prices. These companies are not selling methylene blue that is USP grade and safe for human consumption. This can be detrimental to your health.
How long will one bottle last?
Each bottle of our 1% Methylene Blue has 60 fl oz of product. This would be a 2 month supply when following the serving recommendations on the bottle of 1ml (20 drops) if taken daily.
Are there any precautions for using Methylene Blue?
YES! Do not take Methylene Blue without consulting your healthcare provider if you are on a serotonin reuptake inhibitor, depression/anxiety medications or supplements.
These include: SSRI’s, SNRI’s, or other serotonergic drugs or supplements (St. John’s Wort, 5-HTP, or tryptophan). If taken with these medications it can cause dangerously high serotonin levels, leading to serotonin syndrome – a potentially life-threatening condition.
Methylene Blue does NOT inhibit serotonin itself. It is a potent inhibitor of monoamine oxidase A (MAO-A), an enzyme that breaks down serotonin, dopamine, and norepinephrine in the brain, which can increase serotonin levels by inhibiting its breakdown.
Do NOT take if you have glucose-6-phosphate dehydrogenase deficiency (G6PD). Can cause hemolytic anemia.
Do Not take if you are pregnant or breastfeeding.
May stain skin, dentures, tooth colored restorations & other surfaces. Put dose in an empty gel capsule to prevent staining. Urine may turn green/blue.
Can athletes use Methylene Blue for performance and recovery?
Absolutely! Our methylene blue drops support improved oxygen utilization, reduced fatigue, and enhanced endurance—making them a valuable addition for athletes, fitness enthusiasts, and anyone pursuing peak performance.
Is Methylene Blue safe for long term use?
Yes! Our methylene blue is formulated with pharmaceutical-grade purity to provide safe and effective cellular support. For long term use it is recommended to use for 5 days and take 2 days off each week. As with any supplement regimen, we recommend consulting with a healthcare professional before extended use.
Will Methylene Blue turn my mouth or urine blue?
Yes! It will turn your teeth & mouth blue temporarily. It will come off your natural teeth with brushing, but can stain tooth colored restorations and dentures permanently.
Use an empty gel capsule to put your dose in and swallow it to prevent staining. Make sure to drink 8-12 oz of water when using a capsule.
You can also use a straw to help minimize the blue staining.
Yes! Your urine will usually turn a green to blue color depending on the dosage.
Is there a way to remove the blue color?
To remove the blue color to reduce staining of mouth, teeth and blue colored urine:
Mix ¼ tsp Ascorbic Acid (Vit C Powder) for every 20 drops of Methylene Blue. Mix or let sit until color fades. This can potentially take 10-15 minutes
How Vitamin C Affects Methylene Blue
- Conversion to Leuko-Methylene Blue: Methylene blue is an oxidized compound (dark blue). When combined with antioxidants like Vitamin C, it is converted into leukomethylene blue, which is colorless.
- Enhanced Antioxidant Capacity: The combination is believed to create a "give-and-take" mechanism that assists in maintaining healthy cellular energy and increases the overall antioxidant power, potentially boosting the beneficial effects of both.
- Brain Benefits: Because Vitamin C reduces methylene blue, this pairing is often used to enhance mitochondrial function and support cognitive performance.
- Improved Palatability: Many users combine the two to turn the solution clear, which prevents the "blue mouth" side effect.
As always, please consult your healthcare provider before using any supplement.
How fast does Methylene Blue take effect?
The liquid format allows for rapid absorption, with most users experiencing effects within 30-60 minutes. Methylene Blue's half life is 4-6 hours which means half of the supplement is out of your body in that time frame.
How does Methylene Blue improve cellular energy?
Methylene blue supports your mitochondria (the powerhouse of you cells) by donating electrons during energy production. This helps your cells create ATP (energy) more effectively while improving how efficiently your body uses oxygen. The result is enhanced cellular energy at the source.
Do you provide a COA (lab test results) with your product?
Yes! Our products have a Certificate Of Analysis (COA) which is available upon request. We do not post them publicly to protect our products from individuals who can use them fraudulently. Use this link to contact our support team.
What changes will I notice while taking Methylene Blue?
Many users experience improved energy, mental clarity, and a more positive mood shortly after their first use—often described as an enhanced sense of well-being. Many report a decrease in inflammation and chronic pain. However, individual responses vary.
Some people notice benefits immediately, within a few days or after adjusting their dosage to find their optimal level. Dosage for each individual can be different, so take the time to determine what dose is best for you. Start slowly and increase dosing as tolerated.
Please note that ThistleDew Vitality does not provide medical advice. Always consult with a qualified healthcare professional regarding any health or medical decisions.
Is your Methylene Blue USP-Pharmaceutical grade and free from formaldehyde?
Yes! Our product is carefully manufactured in the USA in an FDA certified cGMP facility with high standards and is tested to USP (United States Pharmacopeia) standards.
Our product is lab tested for the presence of bacteria including E.coli, Salmonella & Staphylococcus along with yeast & mold.
We also test for the presence of heavy metals including arsenic, cadmium, mercury and lead.
Our product is free from formaldehyde and is tested for accuracy in concentration. You can be sure you are getting a safe product intended for human consumption.
Our product label has been FDA reviewed for compliance.
Is Methylene Blue a dye?
Methylene blue is a salt with a history of being used as a dye. It's a chemical compound with the chemical name Methylthioninium Chloride and formula C₁₆H₁₈ClN₃S, which is part of the phenothiazine family. Phenothiazines are a group of medicines that were originally developed to help calm the mind and treat mental health conditions.
It is a synthetic compound with a rich history dating back to 1876, when chemist Heinrich Caro first created it. Initially developed as a textile dye for fabrics and paper, its therapeutic potential was discovered in the late 1800s. It became one of the earliest synthetic medicines, used to treat malaria and various medical conditions including methemoglobinemia and cyanide poisoning.
Today, it's recognized as both a pharmaceutical agent and wellness supplement.